Retinoid Receptor

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Retinoid Receptor製品

• All (33)
• Retinoid Receptor阻害剤 (1)
• Retinoid Receptor拮抗剤(2)
• Retinoid Receptor作動薬(15)
• 新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1653	Retinoic acid (Tretinoin)	Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.	Cell Prolif, 2024, e13762. Cancers (Basel), 2024, 16(6)1178 Cell Res, 2023, 33(6):421-433
S2098	Bexarotene	Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.	J Immunother Cancer, 2024, 12(11)e009805 iScience, 2024, 27(2):108857 Cancer Sci, 2024, 10.1111/cas.16280
S4627	TTNPB	TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Nat Commun, 2024, 15(1):9771 Stem Cell Res Ther, 2024, 15(1):274 Genes (Basel), 2023, 14(4)946
S2933	AM580	AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.	Cell Rep, 2023, 42(6):112566 Cell Res, 2022, 10.1038/s41422-022-00668-0 J Leukoc Biol, 2022, 111(5):1107-1121
S1276	Adapalene	Adapalene (CD-271 is a dual RAR and RXR agonist, used in the treatment of acne.	Int J Mol Sci, 2022, 23(16)9366 Cancer Discov, 2020, 10(7):1058-1077 PLoS Pathog, 2020, 16;16(3):e1008341
S1368	Acitretin	Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.	Int J Mol Sci, 2022, 23(16)9366 Sci Rep, 2021, 11(1):9601 Antimicrob Agents Chemother, 2017, 61(11). pii: e01368-17
S1569	Tazarotene	Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.	Int J Mol Sci, 2022, 23(16)9366 Mol Pharm, 2015, 12(9):3399-407 J Clin Invest, 2013, 123(9):3941-51
S4260	Tamibarotene	Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.	Cancer Sci, 2024, 10.1111/cas.16280 Cancers (Basel), 2024, 16(7)1311 Int J Mol Sci, 2022, 23(16)9366
S2833	UVI 3003	UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR) with IC50 of 0.24 μM against human RXR.	Cell Rep, 2023, 10.1016/j.celrep.2023.113369 Genes (Basel), 2023, 14(4)946
S5233	Fenretinide	Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma).	Acta Pharm Sin B, 2023, 13(1):142-156 Acta Pharm Sin B, 2023, 13(1):142-156
E2813	SR 11237	SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.	Nat Commun, 2024, 15(1):4108 Nat Commun, 2024, 15(1):4108 J Am Heart Assoc, 2023, 12(15):e029415
S4699	Etretinate	Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.	Viruses, 2021, 13(8)1533
E1627New	BMS493	BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro.
E1445	Palovarotene	Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.
S6605	AR7	AR7 is a retinoic acid receptor α (RARα) antagonist.
S6132	All trans-Retinal	All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.
S2520	CD437(AHPN)	CD437(AHPN), a synthetic retinoid, is a selective Retinoic acid Receptor γ ( RARγ) agonist. It exhibits an antiproliferative effect and induces apoptosis via activation of AP-1 in vitro.
E1468	MSU-42011	MSU-42011 is an orally active agonist of retinoid X receptor (RXR). MSU-42011 inhibits the expression of iNOS and p-ERK protein. It exhibits immunomodulatory and antitumor activity. MSU-42011 can be used for cancer research.
S1653	Retinoic acid (Tretinoin)	Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.	Cell Prolif, 2024, e13762. Cancers (Basel), 2024, 16(6)1178 Cell Res, 2023, 33(6):421-433
S2098	Bexarotene	Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.	J Immunother Cancer, 2024, 12(11)e009805 iScience, 2024, 27(2):108857 Cancer Sci, 2024, 10.1111/cas.16280
S4627	TTNPB	TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Nat Commun, 2024, 15(1):9771 Stem Cell Res Ther, 2024, 15(1):274 Genes (Basel), 2023, 14(4)946
S2933	AM580	AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.	Cell Rep, 2023, 42(6):112566 Cell Res, 2022, 10.1038/s41422-022-00668-0 J Leukoc Biol, 2022, 111(5):1107-1121
S1276	Adapalene	Adapalene (CD-271 is a dual RAR and RXR agonist, used in the treatment of acne.	Int J Mol Sci, 2022, 23(16)9366 Cancer Discov, 2020, 10(7):1058-1077 PLoS Pathog, 2020, 16;16(3):e1008341
S1368	Acitretin	Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.	Int J Mol Sci, 2022, 23(16)9366 Sci Rep, 2021, 11(1):9601 Antimicrob Agents Chemother, 2017, 61(11). pii: e01368-17
S1569	Tazarotene	Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.	Int J Mol Sci, 2022, 23(16)9366 Mol Pharm, 2015, 12(9):3399-407 J Clin Invest, 2013, 123(9):3941-51
S4260	Tamibarotene	Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.	Cancer Sci, 2024, 10.1111/cas.16280 Cancers (Basel), 2024, 16(7)1311 Int J Mol Sci, 2022, 23(16)9366
E2813	SR 11237	SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.	Nat Commun, 2024, 15(1):4108 Nat Commun, 2024, 15(1):4108 J Am Heart Assoc, 2023, 12(15):e029415
S4699	Etretinate	Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.	Viruses, 2021, 13(8)1533
E1627New	BMS493	BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro.
E1445	Palovarotene	Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.
S6132	All trans-Retinal	All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.
S2520	CD437(AHPN)	CD437(AHPN), a synthetic retinoid, is a selective Retinoic acid Receptor γ ( RARγ) agonist. It exhibits an antiproliferative effect and induces apoptosis via activation of AP-1 in vitro.
E1468	MSU-42011	MSU-42011 is an orally active agonist of retinoid X receptor (RXR). MSU-42011 inhibits the expression of iNOS and p-ERK protein. It exhibits immunomodulatory and antitumor activity. MSU-42011 can be used for cancer research.
S5233	Fenretinide	Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma).	Acta Pharm Sin B, 2023, 13(1):142-156 Acta Pharm Sin B, 2023, 13(1):142-156
S2833	UVI 3003	UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR) with IC50 of 0.24 μM against human RXR.	Cell Rep, 2023, 10.1016/j.celrep.2023.113369 Genes (Basel), 2023, 14(4)946
S6605	AR7	AR7 is a retinoic acid receptor α (RARα) antagonist.
S1653	Retinoic acid (Tretinoin)	Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.	Cell Prolif, 2024, e13762. Cancers (Basel), 2024, 16(6)1178 Cell Res, 2023, 33(6):421-433
S2098	Bexarotene	Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.	J Immunother Cancer, 2024, 12(11)e009805 iScience, 2024, 27(2):108857 Cancer Sci, 2024, 10.1111/cas.16280
S4627	TTNPB	TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Nat Commun, 2024, 15(1):9771 Stem Cell Res Ther, 2024, 15(1):274 Genes (Basel), 2023, 14(4)946
S2933	AM580	AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.	Cell Rep, 2023, 42(6):112566 Cell Res, 2022, 10.1038/s41422-022-00668-0 J Leukoc Biol, 2022, 111(5):1107-1121
S1276	Adapalene	Adapalene (CD-271 is a dual RAR and RXR agonist, used in the treatment of acne.	Int J Mol Sci, 2022, 23(16)9366 Cancer Discov, 2020, 10(7):1058-1077 PLoS Pathog, 2020, 16;16(3):e1008341
S1368	Acitretin	Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.	Int J Mol Sci, 2022, 23(16)9366 Sci Rep, 2021, 11(1):9601 Antimicrob Agents Chemother, 2017, 61(11). pii: e01368-17
S1569	Tazarotene	Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.	Int J Mol Sci, 2022, 23(16)9366 Mol Pharm, 2015, 12(9):3399-407 J Clin Invest, 2013, 123(9):3941-51
S4260	Tamibarotene	Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.	Cancer Sci, 2024, 10.1111/cas.16280 Cancers (Basel), 2024, 16(7)1311 Int J Mol Sci, 2022, 23(16)9366
E2813	SR 11237	SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.	Nat Commun, 2024, 15(1):4108 Nat Commun, 2024, 15(1):4108 J Am Heart Assoc, 2023, 12(15):e029415
S4699	Etretinate	Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.	Viruses, 2021, 13(8)1533
E1627New	BMS493	BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro.
E1445	Palovarotene	Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.
S6132	All trans-Retinal	All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.
S2520	CD437(AHPN)	CD437(AHPN), a synthetic retinoid, is a selective Retinoic acid Receptor γ ( RARγ) agonist. It exhibits an antiproliferative effect and induces apoptosis via activation of AP-1 in vitro.
E1468	MSU-42011	MSU-42011 is an orally active agonist of retinoid X receptor (RXR). MSU-42011 inhibits the expression of iNOS and p-ERK protein. It exhibits immunomodulatory and antitumor activity. MSU-42011 can be used for cancer research.
E1627New	BMS493	BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro.
E1627New	BMS493	BMS493 is an inverse agonist of pan retinoic acid receptor (RAR). It increases nuclear corepressor interaction with RARs and can be used as an inhibitor for the dietary and pharmacologic manipulation of retinoic acid (RA) activity in vivo and in vitro.