ホームページ Metabolism Retinoid Receptor RAR 選択性 作動薬
  • RAR
  • RXR

RAR 選択性 作動薬

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S4699 Etretinate Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. Selective
S1569 Tazarotene Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. Selective
S4627 TTNPB TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. Selective RARα, IC50: 5.1 nM; RARβ , IC50: 4.5 nM; RARγ, IC50: 9.3 nM
S4260 Tamibarotene Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. Selective
S1276 Adapalene Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne. Pan
S1653 Retinoic acid (Tretinoin) Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Pan