ハイドロトロープ剤

製品コード	製品名	製品説明
S7770	1-Methoxy PMS	Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is a stable electron-transport mediator between NAD(P)H and tetrazolium dyes. Methoxy-PMS receives an electron from NADH or NADPH at the membrane or inside of the cell and passes the electron to the WST-8 that is around the outer cell membrane.
S4592	SBE-β-CD	SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.
S4678	Povidone iodine	Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. Povidone iodine displays excellent antibacterial activity against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. Povidone iodine is used as a topical antiseptic in surgery and for skin and mucous membrane infections, as well as as an aerosol.
S4760	(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD)	(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin) is a well-known sugar used in drug delivery, genetic vectors, environmental protection, and the treatment of Niemann-Pick disease type C1 (NPC1). It is an inhibitor of amyloid-β aggregation and widely used drug delivery vehicle to improve stability and bioavailability.
S6700	Castor oil	Castor oil is a triglyceride derived from Ricinus communis and has been frequently used in antidiarrhea bioassays on laboratory animals. It has been used to study the effects on rat lens conditions. Castor oil has also been used as a test reagent in the rat model of castor oil-induced diarrhoea to study the dose-response relationship and mechanism of action of Saccharomyces boulardii.
S6701	Corn Oil	Corn oil is a refined vegetable oil used as a delivery vehicle for fat-soluble compounds, including toxins. It is also used in the delivery of tamoxifen (TAM) in mice, curcumin in rats, and [3H]retinol in mice.
S6702	Tween 80	Tween 80 is a polysorbate surfactant used for selective protein extraction and the isolation of nuclei from mammalian cell lines. Tween 80 has been used in drug vehicle solutions for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.
S6703	CMC-Na	CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. Its addition possibly increases the hydrogenation and dehydrogenation features of Magnesium.
S6704	PEG300	PEG300 (Polyethylene glycol 300) is a water-miscible polyether widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. It serves as a kind of solubilizer, excipient, lubricant, and chemical reagent. PEG300 helps in the formation of hydrogels in situ upon mixing with silk. These PEG–silk hydrogels are of interest for many biomedical applications, such as anti-fouling and anti-adhesion.
S6705	PEG400	PEG400b (Polyethylene glycol 400) is a commonly used co-solvent used in a variety of pharmaceutical formulations. It acts as a good solubilizer and surfactant and has the potential to improve the bioavailability of drugs. PEG400 significantly accelerates the metabolism of baicalein and increases the penetration of BG and B6G in Caco‐2 cells.
S2428	Isopropyl myristate	Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. It affects the lamellar lipid assembly in terms of bilayer perturbation and disordering.
S2766	Glycerol	Glycerol (Glycerin) is a clear, colourless and viscous liquid that can be used as emollient, solvent or sweetening agent. Glycerol changes the separation characteristics of polyacrylamide nucleoprotein gels and prevents dissociation of nucleosomes and other protein-DNA complexes during electrophoresis.
S6923	NOTA	NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid is a bifunctional chelating agent which acts as the framework to construct PET imaging tools. It is also used for probe design and signal amplification via the multivalent effect and also has potential applications as diagnostic gallium radiopharmaceuticals.
S6962	TPEN	TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn²⁺ signaling. TPEN (TPEDA) may be a potential therapeutic strategy for APL (acute promyelocytic leukemia).TPEN induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.