Influenza Virus

Influenza Virus製品

All (19)
Influenza Virus阻害剤 (17)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S7273	SC75741	SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. SC75741 efficiently blocks influenza virus propagation.	J Transl Med, 2024, 22(1):672 World J Stem Cells, 2024, 16(5):575-590 J Exp Clin Cancer Res, 2023, 42(1):25
S1848	Curcumin	Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.	Cancer Cell Int, 2024, 24(1):303 Front Pharmacol, 2024, 15:1418902 PLoS Negl Trop Dis, 2024, 18(8):e0012428
S7975	Favipiravir (T-705)	Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.	J Med Virol, 2024, 96(1):e29372 Okayama University, 2023 , 10.18926/65391 Nat Commun, 2022, 13(1):2256
S1627	Nitazoxanide	Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.	Nat Commun, 2024, 15(1):8708 Mol Ther, 2024, S1525-0016(24)00340-X Biomed Pharmacother, 2024, 171:116195
S2597	Oseltamivir Phosphate	Oseltamivir Phosphate(Tamiflu) is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.	Clin Immunol, 2024, 262:110178 Front Immunol, 2023, 14:1155880 iScience, 2022, 25(4):104088
S3007	Zanamivir	Zanamivir (GG167,GR 121167X) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.	Front Immunol, 2019, 10:2575 Emerg Microbes Infect, 2014, 3(11):e78 Emerg Microbes Infec, 2014, 3, e78
S2716	Peramivir Trihydrate	Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.	Viruses, 2024, 16(9)1467 Emerg Microbes Infect, 2014, 3(11):e78 Emerg Microbes Infec, 2014, 3, e78
S2120	Arbidol HCl	Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.	mBio, 2024, e0228723. PLoS One, 2022, 17(11):e0276751
S1964	Rimantadine	Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.	J Virol Methods, 2019, 274:113714
S0289	KIN1148	KIN1148 is an agonist of interferon regulatory factor 3 (IRF3) that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances flu vaccine efficacy.	J Allergy Clin Immunol, 2022, S0091-6749(22)01423-3
S0433	Nucleozin	Nucleozin is an antivirus agent that targets influenza A nucleoprotein (NP). Nucleozin triggers the aggregation of NP and inhibits its nuclear accumulation.	Nat Commun, 2022, 13(1):2079
S6854	Triazavirin (TZV)	Triazavirin (TZV) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.	Nature, 2022, 604(7904):120-126
S0861	Laninamivir Octanoate	Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S5499	Amantadine	Amantadine (1-Adamantanamine) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.Amantadine can relieve muscle stiffness, tremors, and movement disorders caused by Parkinson's disease.
S3897	(-)-Arctigenin	(-)-Arctigenin, a lignan found in certain plants of the Asteraceae, exerts biological activities including anti-inflammatory, antiviral and anticancer.
E0207	Chebulinic acid	Chebulinic acid, a phenolic compound isolated from Terminalia chebula fruit, is a novel Influenza viral neuraminidase inhibitor. Chebulinic acid is a antiangiogenic agent through inhibiting the actions of VEGF. Chebulinic acid shows antitumour activity.
S2869	Adamantane	Adamantane is a colorless, crystalline chemical compound first isolated from petroleum with a camphor-like odor. Adamantane is used to treat influenza A virus infections.
S3870	D-Pinitol	D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.
S4491	Cetylpyridinium chloride monohydrate	Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.
S7273	SC75741	SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. SC75741 efficiently blocks influenza virus propagation.	J Transl Med, 2024, 22(1):672 World J Stem Cells, 2024, 16(5):575-590 J Exp Clin Cancer Res, 2023, 42(1):25
S1848	Curcumin	Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.	Cancer Cell Int, 2024, 24(1):303 Front Pharmacol, 2024, 15:1418902 PLoS Negl Trop Dis, 2024, 18(8):e0012428
S7975	Favipiravir (T-705)	Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.	J Med Virol, 2024, 96(1):e29372 Okayama University, 2023 , 10.18926/65391 Nat Commun, 2022, 13(1):2256
S1627	Nitazoxanide	Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.	Nat Commun, 2024, 15(1):8708 Mol Ther, 2024, S1525-0016(24)00340-X Biomed Pharmacother, 2024, 171:116195
S2597	Oseltamivir Phosphate	Oseltamivir Phosphate(Tamiflu) is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.	Clin Immunol, 2024, 262:110178 Front Immunol, 2023, 14:1155880 iScience, 2022, 25(4):104088
S3007	Zanamivir	Zanamivir (GG167,GR 121167X) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.	Front Immunol, 2019, 10:2575 Emerg Microbes Infect, 2014, 3(11):e78 Emerg Microbes Infec, 2014, 3, e78
S2716	Peramivir Trihydrate	Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.	Viruses, 2024, 16(9)1467 Emerg Microbes Infect, 2014, 3(11):e78 Emerg Microbes Infec, 2014, 3, e78
S2120	Arbidol HCl	Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.	mBio, 2024, e0228723. PLoS One, 2022, 17(11):e0276751
S1964	Rimantadine	Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.	J Virol Methods, 2019, 274:113714
S0289	KIN1148	KIN1148 is an agonist of interferon regulatory factor 3 (IRF3) that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances flu vaccine efficacy.	J Allergy Clin Immunol, 2022, S0091-6749(22)01423-3
S0433	Nucleozin	Nucleozin is an antivirus agent that targets influenza A nucleoprotein (NP). Nucleozin triggers the aggregation of NP and inhibits its nuclear accumulation.	Nat Commun, 2022, 13(1):2079
S6854	Triazavirin (TZV)	Triazavirin (TZV) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.	Nature, 2022, 604(7904):120-126
S0861	Laninamivir Octanoate	Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S5499	Amantadine	Amantadine (1-Adamantanamine) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.Amantadine can relieve muscle stiffness, tremors, and movement disorders caused by Parkinson's disease.
E0207	Chebulinic acid	Chebulinic acid, a phenolic compound isolated from Terminalia chebula fruit, is a novel Influenza viral neuraminidase inhibitor. Chebulinic acid is a antiangiogenic agent through inhibiting the actions of VEGF. Chebulinic acid shows antitumour activity.
S2869	Adamantane	Adamantane is a colorless, crystalline chemical compound first isolated from petroleum with a camphor-like odor. Adamantane is used to treat influenza A virus infections.
S4491	Cetylpyridinium chloride monohydrate	Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.

Influenza Virus阻害剤の選択性比較