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MALT

亜型選択性的な製品

MALT製品

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  • MALT阻害剤 (4)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7429 MI-2 (MALT1 inhibitor) MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM.
Adv Healthc Mater, 2024, e2401192.
J Clin Invest, 2023, 133(3)e165694
Int J Mol Sci, 2023, 24(8)7402
S8898 MLT-748 MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state.
E1740New Mepazine hydrochloride Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 aa 325-760. It effectively suppresses the activation of the NF-kB pathway specifically in activated B cell subtype of diffuse large B cell lymphoma (ABC-DLBCL) cells and makes it a promising candidate for the treatment of ABC-DLBCL.
S9896 Safimaltib Safimaltib(JNJ-67856633,JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease.
Cancer Res Commun, 2024, 4(2):312-327.
S7429 MI-2 (MALT1 inhibitor) MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM.
Adv Healthc Mater, 2024, e2401192.
J Clin Invest, 2023, 133(3)e165694
Int J Mol Sci, 2023, 24(8)7402
S8898 MLT-748 MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state.
E1740New Mepazine hydrochloride Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 aa 325-760. It effectively suppresses the activation of the NF-kB pathway specifically in activated B cell subtype of diffuse large B cell lymphoma (ABC-DLBCL) cells and makes it a promising candidate for the treatment of ABC-DLBCL.
S9896 Safimaltib Safimaltib(JNJ-67856633,JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease.
Cancer Res Commun, 2024, 4(2):312-327.
E1740New Mepazine hydrochloride Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 aa 325-760. It effectively suppresses the activation of the NF-kB pathway specifically in activated B cell subtype of diffuse large B cell lymphoma (ABC-DLBCL) cells and makes it a promising candidate for the treatment of ABC-DLBCL.

MALT阻害剤の選択性比較

Tags: MALT inhibitor|MALT agonist|MALT activator|MALT inducer|MALT antagonist|MALT signaling pathway|MALT assay kit