ホームページ DNA Damage/DNA Repair -Epigenetics PARP PARP14 選択性 阻害剤
  • PARP1
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  • Tankyrase-1
  • Tankyrase-2
  • PARP14
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  • TNKS1
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PARP14 選択性 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S8992 RBN012759 RBN012759 is a potent and selective inhibitor of PARP14 with IC50 of <3 nM and 5 nM for human catalytic domain and mouse catalytic domain, respectively. RBN012759 contributes to anti-tumor immune response. Selective human PARP14, IC50: <3 nM; mouse PARP14, IC50: 5 nM
S0732 GeA-69 GeA-69 is a cell-permeable, selective allosteric inhibitor targeting macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) with Kd of 860 nM. Selective PARP14-MD2, Kd: 860 nM