Panitumumab (anti-EGFR)

製品コードA2018 別名: ABX-EGF

製品コード：A2018 純度：99%

Panitumumab (anti-EGFR, ABX-EGF) is a recombinant, fully human IgG2 monoclonal antibody that binds to the epidermal growth factor receptor (EGFR).

サイズ（液体）	価格(税別)	在庫状況
1mg	JPY 44500	国内在庫あり
1mg*5	JPY 146500	お問い合わせ
1mg*25	JPY 445500	お問い合わせ

代表番号: 045-509-1970\|電子メール：sales@selleck.co.jp よく尋ねられる質問

文献中Selleckの製品使用例（2）

質量管理及び製品安全説明書

現在のバッチを見る：純度： 99% タンパク質濃度： 7.09 mg/ml 内毒素：＜1EU/mg

EGFR阻害剤の選択性比較

阻害剤	Citation	EGFR/ErbB1	HER2/ErbB2	ErbB3	ErbB4	mutant EGFR	その他
Saracatinib (AZD0530)	299	+++					c-Src,c-YES,LCK
Canertinib (CI-1033)	48	++++	+++
AG-490	132	+					JAK2 (V617F)
CP-724714	108		++
WZ4002	34	++++
Sapitinib (AZD8931)	48	+++	+++	+++
CUDC-101	23	+++	++				HDAC,HDAC1,HDAC6
AG-1478	97	+++
PD153035 HCl	17	++++
Pelitinib (EKB-569)	11	+	+				Src,MEK/ERK,Raf
AEE788 (NVP-AEE788)	13	++++	+++		+		c-Abl,FLT1,c-Fms
AC480 (BMS-599626)	10	++	++		+
AP26113-analog (ALK-IN-1)	4					++	ALK,IGF1R,INSR
WZ3146	2	++++
Allitinib tosylate	16	++++	+++		++++
Rociletinib (CO-1686)	36	++
Varlitinib	8	+++	++++
Icotinib (BPI-2009H)	9	+++
TAK-285	4	++	++		+		MEK1,Aurora B,LCK
WHI-P154	11	+++					Src,VEGFR,JAK3
Daphnetin	4	+					PKA,PKC
PD168393	6	++++
CNX-2006	2	++				++
Tyrphostin 9	1	+					PDGFR
AG-18	1	+
Icotinib Hydrochloride	0	+++
HS-10296 hydrochloride	0					++++
MTX-531	0	++					PI3Kα
Avitinib maleate	0	+++				++++	BTK
limertinib	0					++++
AG 825	0		+				PDGFR
4-AMino-1-phenylpyrazolo[3,4-d]pyriMidine	0	+
AST-1306	0	++++	+++		++++
ErbB2 inhibitor	0		+		+
Tuxobertinib (BDTX-189)	2	++++	++++				RIPK2,BLK
Epertinib hydrochloride	0	++++	+++		+++
JND3229	0	+++				++	EGFR C797S
BI-4020	1					++++
Tyrphostin AG-528	0	+	+
AG 556	0	+
Canertinib dihydrochloride	8	+++	+++
EGFR Inhibitor	3	++					Microtubules
SU5214	0	+					VEGFR2
RG 13022	0	+
TQB3804	0					++++
zipalertinib (TAS6417)	3	+++			+++	++++	TXK,BMX
Pyrotinib dimaleate	4	++	++
PD153035	14	++++
AG 494	0	+
AG 555	0	+
Theliatinib (HMPL-309)	0	+++				++
Avitinib (Abivertinib)	2					++++	JAK3,BTK
Lazertinib	7	++++				++++	Del19,L85R
Lifirafenib (BGB-283)	6	++				+	WT A-RAF,C-RAF (Y340/341D),BRAF(V600E)
Nazartinib (EGF816)	6	++				++
Zorifertinib (AZD3759)	6	++++
CL-387785 (EKI-785)	5	++++
Poziotinib	34	+++	+++		++
AZ5104	4	++++			+++		ACK1,BLK,BRK
AV-412 free base	0	++++	++			++++
HER2-Inhibitor-1	1		✔
WZ8040	2	✔
Genistein	32	✔					topo II
Rezivertinib	0	✔
BDTX-1535	0	✔
Falnidamol	0	✔
BLU-945	0	✔
(S)-Sunvozertinib ((S)-DZD9008)	1	✔
Licochalcone D	0	✔					NF-κB,PARP,Caspase
Alflutinib (Furmonertinib) mesylate	2	✔					CYP3A4
(Rac)-JBJ-04-125-02	0	✔
Tyrphostin AG30 (AG30)	0	✔
AG-1557	0	✔
AG99	0	✔
MTX-211	2	✔					PI3K
RG14620	0	✔					ABCG2
Almonertinib (HS-10296)	2					✔
Cyasterone	1	✔
Norcantharidin	3	✔					c-Met
Naquotinib(ASP8273)	1	✔
EAI045	2					✔
Olmutinib (BI 1482694)	5	✔					BTK
Butein	2	✔
Chrysophanic Acid	3	✔					mTOR
EGCG ((-)-Epigallocatechin Gallate)	41	✔					DNMT,telomerase,FASN

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

生物活性

製品説明	Panitumumab (anti-EGFR, ABX-EGF) is a recombinant, fully human IgG2 monoclonal antibody that binds to the epidermal growth factor receptor (EGFR).

参考
[1] Wells A Messersmith, et al. Clin Cancer Res . 2007 Aug 15;13(16):4664-6.

参考

[1] Wells A Messersmith, et al. Clin Cancer Res . 2007 Aug 15;13(16):4664-6.

製品説明

CAS No.	339177-26-3
Molecular Weight	144 kD
Formulation	PBS Buffer, PH 7.4
Isotype	Human IgG2
Source	CHO cells
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered

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Handling Instructions

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