Mogamulizumab (Anti-CCR4 / CD194)

製品コードA2568 別名: KW-0761

製品コード：A2568 純度：99%

Mogamulizumab (Anti-CCR4 / CD194) is a defucosylated humanized recombinant monoclonal antibody targeting CCR4. Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL). MW:145.5 KD.

サイズ（液体）	価格(税別)	在庫状況
1mg	JPY 44500	国内在庫あり
1mg*5	JPY 146500	お問い合わせ
1mg*25	JPY 445500	お問い合わせ

代表番号: 045-509-1970\|電子メール：sales@selleck.co.jp よく尋ねられる質問

質量管理及び製品安全説明書

現在のバッチを見る： A256801 純度： 99% タンパク質濃度： 6.86mg/ml 内毒素：＜1EU/mg

CCR阻害剤の選択性比較

阻害剤	Citation	CCR	CCR1	CCR2	CCR3	CCR4	CCR5	CCR9	CCL	その他
SB-328437	0				++
INCB3344	4			++						mCCR2
RS504393	1			+
C-021	0					+
Vercirnon	0							+++
BX471	1		++++
PF-4136309	0			++
Vicriviroc maleate	1	+++					+++
RS-102895 Hydrochloride	0			+						human α1a receptor,human α1d receptor,5-HT1a receptor
RS102895	2			+
TAK-779	0	++++					++++			CXCR3
AZD2098	1					++
Adaptavir (DAPTA)	3	++++					++++
R243	0	✔
Perillaldehyde	0								✔	NRF2/HO1,ROS,AhR
Cenicriviroc	8			✔						HIV-2,HIV-1
Isuzinaxib (APX-115 free base)	0								✔	TNFα,IL-6,NOX2
SB-297006	2				✔
BMS-813160	2			✔
Bindarit	23								✔

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

生物活性

製品説明	Mogamulizumab (Anti-CCR4 / CD194) is a defucosylated humanized recombinant monoclonal antibody targeting CCR4. Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL). MW:145.5 KD.

製品説明

CAS No.	1159266-37-1
Molecular Weight	144.12 kDa
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Isotype	Human IgG1
Source	CHO
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Purification	AKTA
Sterility	0.2 μM filtered

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

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