gp91ds-tat

製品コード：P1213 純度：99.95%

gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.

Amino-acid Sequence

CAS No.

サイズ	価格(税別)	在庫状況
5mg	JPY 22000	国内在庫あり
25mg	JPY 62500	国内在庫あり
100mg	JPY 145500	お問い合わせ
1g	JPY 598500	お問い合わせ
バルクサイズ	バルク特価あり

代表番号: 045-509-1970\|電子メール：[email protected] よく尋ねられる質問

製品安全説明書

現在のバッチを見る： P121301 Water] 49 mg/mL] false] ] ] false] ] ] false 純度： 99.95%

99.95

化学情報

保管	3 years-20°C powder	溶液の保管冷凍と解凍の繰り返しを避けるため小分けにしてください	1年-80°Cin solvent
			１ケ月-20°Cin solvent

In vitro
Batch:

Water : 49 mg/mL

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明

Targets

NADPH oxidase

In vitro
In vitro	Gp91ds-tat, an inhibitor of NOX (NADPH oxidase) 2, can prevented high extracellular glucose (Hi-Glu)/Thiamet G (ThmG)-induced ROS generation.^[2]

In Vivo
In vivo	Gp91ds-tat can attenuate cerebral I/R injury in a rat model of middle cerebral artery occlusion (MCAO) through reducing ROS levels, inhibiting neuronal apoptosis and degeneration, and alleviating BBB damage.^[3]
動物実験	動物モデル	middle cerebral artery occlusion (MCAO) model rats
	投与量	100 ng/kg
	投与経路	infused into the ventricle

参考
[1] Lopes N, et al. Mol Cell Biol. 2003 Aug;23(15):5401-8. [2] Lu S, et al. Circ Res. 2020 May 8;126(10):e80-e96. [3] Wang J, et al. Acta Neurochir Suppl. 2020;127:47-54.

参考

製品情報

Molecular Formula	C₁₀₉H₂₀₂N₅₂O₂₅S₁
Molecular Weight	2673.3
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)