Carperitide Acetate

製品コード：P1087 純度：99%

Caperitide acetate is a synthetic analog of human atrial natriuretic peptide (ANP) containing 28 amino acids. It acts as an inhibitor of endothelin-1 secretion when stimulated by angiotensin II (Ang II), likely through a cGMP-dependent mechanism.It induces natriuresis, diuresis, and vasodilation, effectively reducing blood volume and easing cardiac strain. By suppressing the renin-angiotensin-aldosterone system (RAAS), it aids in preventing myocardial remodeling and fibrosis, thereby enhancing cardiac function and decreasing the incidence of postoperative atrial fibrillation, heart failure, and stroke. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.

Amino-acid Sequence

CAS No. 1366000-58-9

サイズ	価格(税別)	在庫状況
1mg	JPY 52000	国内在庫あり
5mg	JPY 144500	国内在庫あり
バルクサイズ	バルク特価あり

代表番号: 045-509-1970\|電子メール：[email protected] よく尋ねられる質問

製品安全説明書

現在のバッチを見る：純度： 99%

化学情報

保管	3 years-20°C powder	溶液の保管冷凍と解凍の繰り返しを避けるため小分けにしてください	1年-80°Cin solvent
			１ケ月-20°Cin solvent

In vitro
Batch:

Water : 60 mg/mL

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明

Targets

NPR-A

10.8 nM

参考
[1] Kohno M, et al. Circ Res. 1992 Feb;70(2):241-7. [2] Sezai A, et al. Circ Arrhythm Electrophysiol. 2015 Jun;8(3):546-53.

参考

製品情報

Molecular Formula	C₁₂₉H₂₀₇N₄₅O41S₃
Molecular Weight	3140.49
CAS No.	1366000-58-9
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)