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Apamin

Apamin, an 18 amino acid peptide neurotoxin present in apitoxin (bee venom), has been shown to have anti-inflammatory and anti-fibrotic properties. It is known to be a highly selective blocker of Ca2+-activated K+ (SK) channels and then lessen the expression of α-SMA in the TGF-β1-induced HSC-T6 cells.

Amino-acid Sequence

Apamin化学構造

CAS No. 24345-16-2

サイズ 価格(税別) 在庫状況
5mg JPY 100500 国内在庫あり
25mg JPY 295500 国内在庫あり
100mg JPY 745500 国内在庫なし(納期7~10日)
バルクサイズ バルク特価あり

代表番号: 045-509-1970|電子メール：[email protected]
よく尋ねられる質問

製品安全説明書

現在のバッチを見る： 純度： 99.93%
99.93

化学情報

保管 3 years-20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (49.32 mM)； 吸湿したDMSOは溶解度を減少させます。新しいDMSOをご使用ください。)

Water : 100 mg/mL

Ethanol : Insoluble

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

生物活性

製品説明 Apamin, an 18 amino acid peptide neurotoxin present in apitoxin (bee venom), has been shown to have anti-inflammatory and anti-fibrotic properties. It is known to be a highly selective blocker of Ca2+-activated K+ (SK) channels and then lessen the expression of α-SMA in the TGF-β1-induced HSC-T6 cells.
Targets
Potassium channel

製品情報

Molecular Formula

C79H131N31O24S4
Molecular Weight 2027.35
CAS No. 24345-16-2
Appearance White Powder
Peptide Content (by %N) ≥80%
Single Impurity (by HPLC) ≤1.0%
Assay (By Anhydrous, Acetic Acid-free) 95.0~105.0%
MS Consistent
Packing plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt)		 3 years -20°C powder； 1 years -80°C in solvent
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)