Apamin

製品コード：P1234 純度：99.93%

Apamin, an 18 amino acid peptide neurotoxin present in apitoxin (bee venom), has been shown to have anti-inflammatory and anti-fibrotic properties. It is known to be a highly selective blocker of Ca²⁺-activated K⁺ (SK) channels and then lessen the expression of α-SMA in the TGF-β1-induced HSC-T6 cells.

Amino-acid Sequence

CAS No. 24345-16-2

サイズ	価格(税別)	在庫状況
5mg	JPY 100500	国内在庫あり
25mg	JPY 295500	国内在庫あり
100mg	JPY 745500	国内在庫なし(納期7~10日)
バルクサイズ	バルク特価あり

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製品安全説明書

現在のバッチを見る：純度： 99.93%

99.93

化学情報

保管	3 years-20°C powder	溶液の保管冷凍と解凍の繰り返しを避けるため小分けにしてください	1年-80°Cin solvent
			１ケ月-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (49.32 mM)；吸湿したDMSOは溶解度を減少させます。新しいDMSOをご使用ください。)

Water : 100 mg/mL

Ethanol : Insoluble

モル濃度計算器

in vivo
Batch:

Add solvents to the product individually and in order.

投与溶液組成計算機

Clear solution

5%DMSO 1 40%PEG300 Click to order 2 5%Tween 80 Click to order 3 50%ddH2O

5.0mg/ml (2.47mM)

Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.

Clear solution

5% DMSO 1 95% Corn oil

0.83mg/ml (0.41mM)

Taking the 1 mL working solution as an example, add 50 μL of 16.6 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

生物活性

製品説明

Targets

Potassium channel

参考
[1] Kim JY, et al. Int J Mol Med. 2017 May;39(5):1188-1194.

参考

[1] Kim JY, et al. Int J Mol Med. 2017 May;39(5):1188-1194.

製品情報

Molecular Formula	C₇₉H₁₃₁N₃₁O₂₄S₄
Molecular Weight	2027.35
CAS No.	24345-16-2
Appearance	White Powder
Peptide Content (by %N)	≥80%
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years -20°C powder； 1 years -80°C in solvent
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)