CPT

亜型選択性的な製品

CPT製品

• All (5)
• CPT阻害剤 (2)
• CPT活性剤(1)
• CPT作動薬(1)
• 新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S8244	Etomoxir sodium salt	Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.	Bioact Mater, 2024, 35:549-563 Cell Chem Biol, 2024, 31(10):1772-1786.e5 Oncogene, 2024, 43(6):406-419
S9819	C75	C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.	PLoS Pathog, 2024, 20(5):e1012228 Theranostics, 2023, 13(13):4482-4496 Theranostics, 2023, 10.7150/thno.84921
S6959	Perhexiline maleate	Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).	Cancer Cell, 2022, S1535-6108(22)00312-9
S2269	Baicalin	Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). Baicalin reduces the expression of NF-κB.	Ecotoxicol Environ Saf, 2024, 275:116262 Chem Biol Interact, 2024, 387:110820 Int J Mol Sci, 2023, 24(11)9435
S9819	C75	C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.	PLoS Pathog, 2024, 20(5):e1012228 Theranostics, 2023, 13(13):4482-4496 Theranostics, 2023, 10.7150/thno.84921
S8244	Etomoxir sodium salt	Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.	Bioact Mater, 2024, 35:549-563 Cell Chem Biol, 2024, 31(10):1772-1786.e5 Oncogene, 2024, 43(6):406-419
S6959	Perhexiline maleate	Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).	Cancer Cell, 2022, S1535-6108(22)00312-9
S2269	Baicalin	Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). Baicalin reduces the expression of NF-κB.	Ecotoxicol Environ Saf, 2024, 275:116262 Chem Biol Interact, 2024, 387:110820 Int J Mol Sci, 2023, 24(11)9435
S9819	C75	C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.	PLoS Pathog, 2024, 20(5):e1012228 Theranostics, 2023, 13(13):4482-4496 Theranostics, 2023, 10.7150/thno.84921