BET

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S6993

(+)-JQ1 carboxylic acid

(+)-JQ1 carboxylic acid ((+)-JQ1-COOH) is a (+)-JQ1 with a carboxylic acid functional group. (+)-JQ1 carboxylic acid ((+)-JQ1-COOH) can be used as a precursor to a PROTAC that targets BET bromodomains after conjugation to a linker and E3 ligase ligand.

J Immunother Cancer, 2023, 11(4)e006070

J Immunother Cancer, 2023, 11(4)e006070

BET阻害剤の選択性比較

Tags: BET inhibitor|BET agonist|BET activator|BET inducer|BET antagonist|BET signaling pathway|BET assay kit