Aminopeptidase

Aminopeptidase製品

All (3)
Aminopeptidase阻害剤 (3)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S9631	Puromycin aminonucleoside	Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.	Cell Mol Biol Lett, 2023, 28(1):62 Cell Mol Biol Lett, 2023, 28(1):62 Oral Dis, 2022, 10.1111/odi.14321
S1522	Tosedostat (CHR2797)	Tosedostat (CHR2797) is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.	PLoS One, 2018, 13(1):e0190682 Integr Biol, 2014, 6(2):164-74 Anal Chem, 2013, 85(10):4991-7
E4916^New	Bestatin hydrochloride	Bestatin hydrochloride is an inhibitor of aminopeptidase N and enkephalinase that elevates the levels of angiotensin II and angiotensin III. It also acts as a non-competitive inhibitor (α > 1) of porcine DPP-IV with a Ki value of 75 μM. It reduces DPP-IV activity, decreases cell viability, and increases DNA fragmentation in vitro. It has the potential to treat skin conditions like acne, psoriasis and keloids.
S9631	Puromycin aminonucleoside	Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.	Cell Mol Biol Lett, 2023, 28(1):62 Cell Mol Biol Lett, 2023, 28(1):62 Oral Dis, 2022, 10.1111/odi.14321
S1522	Tosedostat (CHR2797)	Tosedostat (CHR2797) is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.	PLoS One, 2018, 13(1):e0190682 Integr Biol, 2014, 6(2):164-74 Anal Chem, 2013, 85(10):4991-7
E4916^New	Bestatin hydrochloride	Bestatin hydrochloride is an inhibitor of aminopeptidase N and enkephalinase that elevates the levels of angiotensin II and angiotensin III. It also acts as a non-competitive inhibitor (α > 1) of porcine DPP-IV with a Ki value of 75 μM. It reduces DPP-IV activity, decreases cell viability, and increases DNA fragmentation in vitro. It has the potential to treat skin conditions like acne, psoriasis and keloids.
E4916^New	Bestatin hydrochloride	Bestatin hydrochloride is an inhibitor of aminopeptidase N and enkephalinase that elevates the levels of angiotensin II and angiotensin III. It also acts as a non-competitive inhibitor (α > 1) of porcine DPP-IV with a Ki value of 75 μM. It reduces DPP-IV activity, decreases cell viability, and increases DNA fragmentation in vitro. It has the potential to treat skin conditions like acne, psoriasis and keloids.

Aminopeptidase阻害剤の選択性比較