VMAT antagonist | VMAT inhibitor | VMAT agonist

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S1601	Reserpine	Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.Reserpine can be used to induce animal models of Gastric and Intestinal Ulcers.	J Immunother Cancer, 2024, 12(11)e009805 Int J Mol Sci, 2022, 23(9)4597 Int J Mol Sci, 2022, 23(22)13809
S9500	Valbenazine tosylate	Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).	Cell Rep Med, 2023, 4(10):101208
E4844^New	Valbenazine	Valbenazine(Ingrezza, Mt-5199, NBI-98854, VBZ) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki of 110–190 nM. It is used to treat tardive dyskinesia and chorea associated with Huntington's disease.
S1601	Reserpine	Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.Reserpine can be used to induce animal models of Gastric and Intestinal Ulcers.	J Immunother Cancer, 2024, 12(11)e009805 Int J Mol Sci, 2022, 23(9)4597 Int J Mol Sci, 2022, 23(22)13809
S9500	Valbenazine tosylate	Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).	Cell Rep Med, 2023, 4(10):101208
E4844^New	Valbenazine	Valbenazine(Ingrezza, Mt-5199, NBI-98854, VBZ) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki of 110–190 nM. It is used to treat tardive dyskinesia and chorea associated with Huntington's disease.
E4844^New	Valbenazine	Valbenazine(Ingrezza, Mt-5199, NBI-98854, VBZ) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki of 110–190 nM. It is used to treat tardive dyskinesia and chorea associated with Huntington's disease.

VMAT

VMAT製品

VMAT阻害剤の選択性比較