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Nucleoside Analog/Antimetabolite
Nucleoside Analog/Antimetabolite製品
- All (15)
- Nucleoside Analog/Antimetabolite阻害剤 (6)
- 新製品
| 製品コード | 製品名称 | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
|---|---|---|---|---|
| S1714 | Gemcitabine | Gemcitabine, a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis. |
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| S1209 | 5-FU (5-Fluorouracil) | 5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV. |
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| S1200 | Decitabine | Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines. |
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| S1491 | Fludarabine | Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis. |
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| S1149 | Gemcitabine HCl | ゲムシタビン塩酸塩 (Gemcitabine (LY-188011, NSC 613327) HCl) は DNA 合成阻害剤であり、 PANC1 細胞、 MIAPaCa2 細胞、 BxPC3 細胞および Capan2 細胞における IC50 はそれぞれ 50 nM, 40 nM, 18nM, 12 nM です。 |
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| S1782 | Azacitidine (5-Azacytidine) | Azacitidine (5-Azacytidine, 5-AzaC, Ladakamycin, AZA, 5-Aza, CC-486,NSC 102816) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Azacitidine induces mitochondrial apoptosis and autophagy. |
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| S1648 | Cytarabine | Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis. |
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| S1807 | Acyclovir (Aciclovir) | Acyclovir (Aciclovir) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells. |
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| S1647 | Adenosine | Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. | ||
| S2053 | Cytidine | Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA. | ||
| S2439 | Guanosine | Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. | ||
| S3702 | Dihydrothymine | Dihydrothymine is an intermediate breakdown product of thymine. | ||
| S6854 | Triazavirin (TZV) | Triazavirin (TZV) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza. | ||
| E2919 | 5-Chloro-2'-deoxyuridine | 5-chloro-2′-deoxyuridine (5-chlorodeoxyuridine; CldU), a thymine analog, is used to study the potential of hypochlorous acid damage to DNA and DNA precursors. | ||
| S6138 | 5-Methylcytidine | 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It is found in ribonucleic acids of animal, plant, and bacterial origin. | ||
| S1209 | 5-FU (5-Fluorouracil) | 5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV. |
|
|
| S1200 | Decitabine | Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines. |
|
|
| S1491 | Fludarabine | Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis. |
|
|
| S1149 | Gemcitabine HCl | ゲムシタビン塩酸塩 (Gemcitabine (LY-188011, NSC 613327) HCl) は DNA 合成阻害剤であり、 PANC1 細胞、 MIAPaCa2 細胞、 BxPC3 細胞および Capan2 細胞における IC50 はそれぞれ 50 nM, 40 nM, 18nM, 12 nM です。 |
|
|
| S1648 | Cytarabine | Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis. |
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|
| S1807 | Acyclovir (Aciclovir) | Acyclovir (Aciclovir) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells. |
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Nucleoside Analog/Antimetabolite阻害剤の選択性比較
Tags: Nucleoside Analog/Antimetabolite inhibitor|Nucleoside Analog/Antimetabolite agonist|Nucleoside Analog/Antimetabolite activator|Nucleoside Analog/Antimetabolite inducer|Nucleoside Analog/Antimetabolite antagonist|Nucleoside Analog/Antimetabolite signaling pathway|Nucleoside Analog/Antimetabolite assay kit
納期 国内在庫品：受注日の翌日（15時までの受注分） ＊北海道、九州、沖縄への配送は受注日より２日以上 を要する場合あり 海外在庫品：受注後１〜２週間