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S8222 AS1842856 AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form. AS1842856 suppresses autophagy.
Transl Res, 2024, S1931-5244(24)00051-3
CNS Neurosci Ther, 2024, 30(8):e14913
Cancer Res Commun, 2024, 4(5):1189-1198
S8222 AS1842856 AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form. AS1842856 suppresses autophagy.
Transl Res, 2024, S1931-5244(24)00051-3
CNS Neurosci Ther, 2024, 30(8):e14913
Cancer Res Commun, 2024, 4(5):1189-1198

FOX阻害剤の選択性比較

Tags: FOX inhibitor | FOX antibody | FOX Review | FOX regulation