PARP1
PARP2
PARP3
Tankyrase-1
Tankyrase-2
PARP14
PARP7
TNKS1
TNKS2

TNKS1 阻害剤

製品コード	製品名	製品説明	Selective / Pan	IC50 / Ki
S6739	MN 64	MN-64 is a potent inhibitor of TNKS1 and TNKS2 with IC50 value of 6 and 72 nM, respectively.	Pan	TNKS1, IC50: 6 nM
S1180	XAV-939	XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.	Pan	TNKS1, IC50: 11 nM
S7239	G007-LK	G007-LK is a potent and selective tankyrase inhibitor with IC50 of 46 nM and 25 nM for TNKS1/2, respectively.	Pan	TNKS1, IC50: 46 nM