TET
DNMT1
DNMT3

TET 選択性阻害剤

製品コード	製品名	製品説明	Selective / Pan	IC50 / Ki
S6682	Bobcat339 hydrochloride	Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.	Selective	TET1, IC50: 33 μM; TET2, IC50: 73 μM