SIRT1
SIRT2
SIRT3
SIRT6
SIRT5

SIRT3 阻害剤

製品コード	製品名	製品説明	Selective / Pan	IC50 / Ki
S8628	3-TYP	3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively.	Pan	SIRT3, IC50: 16 nM
S4900	Tenovin-6	Tenovin-6 is a small molecule activator of p53 transcriptional activity and inhibits dihydroorotate dehydrogenase (DHODH). Tenovin-6 is also an inhibitor of SirT1 and SirT2.	Pan	SIRT3, IC50: 67 μM