ホームページ Neuronal Signaling CaMK PKD 選択性 阻害剤
  • CaMKII
  • CaMKIII
  • CaMKKα
  • CaMKKβ
  • PKD

PKD 選択性 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S2642 1-Naphthyl PP1(1-NA-PP1) 1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively. Selective PKD1, IC50: 154.6 nM; PKD2, IC50: 133.4 nM; PKD3, IC50: 109.4 nM
S7188 CID755673 CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs. Selective PKD1, IC50: 180 nM; PKD2, IC50: 280 nM; PKD3, IC50: 227 nM