PKD

PKD製品

  • All (4)
  • PKD阻害剤 (4)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S7188 CID755673 CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.
Nat Commun, 2023, 14(1):3543
Nat Commun, 2023, 14(1):3543
Oncogene, 2023, 42(39):2878-2891
S8366 CRT0066101 dihydrochloride CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.
Cell Rep, 2023, 42(9):113035
Cells, 2023, 12(2)212
NAR Cancer, 2023, 5(2):zcad027
S5792 CID 2011756 CID 2011756 is an inhibitor of protein kinase D (PKD) with IC50 values of 3.2, 0.6, and 0.7 μM for PKD1, PKD2, and PKD3, respectively.
S2642 1-Naphthyl PP1(1-NA-PP1) 1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
S7188 CID755673 CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.
Nat Commun, 2023, 14(1):3543
Nat Commun, 2023, 14(1):3543
Oncogene, 2023, 42(39):2878-2891
S8366 CRT0066101 dihydrochloride CRT0066101 dihydrochloride is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.
Cell Rep, 2023, 42(9):113035
Cells, 2023, 12(2)212
NAR Cancer, 2023, 5(2):zcad027
S5792 CID 2011756 CID 2011756 is an inhibitor of protein kinase D (PKD) with IC50 values of 3.2, 0.6, and 0.7 μM for PKD1, PKD2, and PKD3, respectively.
S2642 1-Naphthyl PP1(1-NA-PP1) 1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.

PKD阻害剤の選択性比較

Tags: PKD inhibitor|PKD agonist|PKD activator|PKD inducer|PKD antagonist|PKD signaling pathway|PKD assay kit