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PAD

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PAD製品

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  • PAD阻害剤 (4)
  • 新製品
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S8141 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Nat Commun, 2024, 15(1):8663
Diabetes, 2024, db231000
Heliyon, 2024, 10(1):e23633
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Eur J Pharmacol, 2024, S0014-2999(24)00322-4
Cell Discov, 2023, 9(1):104
Cell Discov, 2023, 9(1):104
S9644 BMS-P5 BMS-P5, a potent selective pharmacological inhibitor of PAD4, is used to evaluate the effect of PAD4 inhibition on multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation.
S7802New GSK199 GSK199 is a reversible, specific inhibitor of peptidyl arginine deiminase 4 (PAD4), with an IC50 of 200 nM without calcium. It is involved in histone citrullination and neutrophil extracellular trap formation, making it useful for studying autoimmune, cardiovascular, and oncological diseases.
S8141 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Nat Commun, 2024, 15(1):8663
Diabetes, 2024, db231000
Heliyon, 2024, 10(1):e23633
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Eur J Pharmacol, 2024, S0014-2999(24)00322-4
Cell Discov, 2023, 9(1):104
Cell Discov, 2023, 9(1):104
S9644 BMS-P5 BMS-P5, a potent selective pharmacological inhibitor of PAD4, is used to evaluate the effect of PAD4 inhibition on multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation.
S7802New GSK199 GSK199 is a reversible, specific inhibitor of peptidyl arginine deiminase 4 (PAD4), with an IC50 of 200 nM without calcium. It is involved in histone citrullination and neutrophil extracellular trap formation, making it useful for studying autoimmune, cardiovascular, and oncological diseases.
S7802New GSK199 GSK199 is a reversible, specific inhibitor of peptidyl arginine deiminase 4 (PAD4), with an IC50 of 200 nM without calcium. It is involved in histone citrullination and neutrophil extracellular trap formation, making it useful for studying autoimmune, cardiovascular, and oncological diseases.

PAD阻害剤の選択性比較

Tags: PAD inhibitor|PAD agonist|PAD activator|PAD inducer|PAD antagonist|PAD signaling pathway|PAD assay kit