p97

p97製品

All (7)
p97阻害剤 (7)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S7285	NMS-873	NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM).	Cell, 2024, 187(21):6055-6070.e22 Cell, 2024, 187(21):5967-5980.e17 Nat Cell Biol, 2024, 10.1038/s41556-024-01394-y
S8101	CB-5083	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.	Cell, 2024, 187(20):5698-5718.e26 Nat Cell Biol, 2024, 10.1038/s41556-024-01401-2 Proc Natl Acad Sci U S A, 2024, 121(36):e2408787121
S7199	DBeQ	DBeQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.	Cell Mol Immunol, 2024, 10.1038/s41423-024-01222-1 Virol Sin, 2023, 38(4):497-507 Virol J, 2022, 19(1):90
S4921	MNS (3,4-Methylenedioxy-β-nitrostyrene)	MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.	Phytomedicine, 2019, 61:152859 J Biomol Struct Dyn, 2019, 10.1080/07391102.2019.1640133 Toxicol Res (Camb), 2016, 5(1):188-196
S9865	CB-5339	CB-5339 is a potent p97/Valosin Containing Protein (VCP) inhibitor with an IC50 of 9 nM.	Cell Rep, 2023, 42(11):113318
S4453	NPD8733	NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration that specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family.
S0220	ML240	ML240 is an ATP-competitive inhibitor of p97 ATPase with an IC50 of 0.11 μM and a Ki of 0.22 μM.
S7285	NMS-873	NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM).	Cell, 2024, 187(21):6055-6070.e22 Cell, 2024, 187(21):5967-5980.e17 Nat Cell Biol, 2024, 10.1038/s41556-024-01394-y
S8101	CB-5083	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.	Cell, 2024, 187(20):5698-5718.e26 Nat Cell Biol, 2024, 10.1038/s41556-024-01401-2 Proc Natl Acad Sci U S A, 2024, 121(36):e2408787121
S7199	DBeQ	DBeQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.	Cell Mol Immunol, 2024, 10.1038/s41423-024-01222-1 Virol Sin, 2023, 38(4):497-507 Virol J, 2022, 19(1):90
S4921	MNS (3,4-Methylenedioxy-β-nitrostyrene)	MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.	Phytomedicine, 2019, 61:152859 J Biomol Struct Dyn, 2019, 10.1080/07391102.2019.1640133 Toxicol Res (Camb), 2016, 5(1):188-196
S9865	CB-5339	CB-5339 is a potent p97/Valosin Containing Protein (VCP) inhibitor with an IC50 of 9 nM.	Cell Rep, 2023, 42(11):113318
S4453	NPD8733	NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration that specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family.
S0220	ML240	ML240 is an ATP-competitive inhibitor of p97 ATPase with an IC50 of 0.11 μM and a Ki of 0.22 μM.

p97阻害剤の選択性比較

p97シグナル伝達経路

p97シグナル伝達経路

Tags: p97 inhibitor|p97 agonist|p97 activator|p97 inducer|p97 antagonist|p97 signaling pathway|p97 assay kit