Nur77

Nur77製品

All (6)
Nur77拮抗剤(2)
Nur77作動薬(2)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S6674	Cytosporone B	Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278 nM.	Mol Med, 2023, 29(1):63 Mol Med, 2023, 29(1):63 Signal Transduct Target Ther, 2021, 6(1):133
S0149	C-DIM5	C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. C-DIM5 (DIM-C-pPhOCH3) decreases survival and induces apoptosis in RKO colon cancer cells.	Cell Rep Med, 2024, S2666-3791(24)00234-9 Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6799	DIM-C-pPhOH	DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.	Cell Rep, 2024, 43(2):113746 Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6785	DIM-C-pPhCO2Me	DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist with antineoplastic activity.
S6674	Cytosporone B	Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278 nM.	Mol Med, 2023, 29(1):63 Mol Med, 2023, 29(1):63 Signal Transduct Target Ther, 2021, 6(1):133
S0149	C-DIM5	C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. C-DIM5 (DIM-C-pPhOCH3) decreases survival and induces apoptosis in RKO colon cancer cells.	Cell Rep Med, 2024, S2666-3791(24)00234-9 Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6799	DIM-C-pPhOH	DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.	Cell Rep, 2024, 43(2):113746 Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6785	DIM-C-pPhCO2Me	DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist with antineoplastic activity.
S6674	Cytosporone B	Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278 nM.	Mol Med, 2023, 29(1):63 Mol Med, 2023, 29(1):63 Signal Transduct Target Ther, 2021, 6(1):133
S0149	C-DIM5	C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. C-DIM5 (DIM-C-pPhOCH3) decreases survival and induces apoptosis in RKO colon cancer cells.	Cell Rep Med, 2024, S2666-3791(24)00234-9 Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8

Nur77阻害剤の選択性比較