NCX

亜型選択性的な製品

NCX1 NCX2 NCX3

NCX製品

All (6)
NCX阻害剤 (6)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S4643	KB-R7943 mesylate	KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCX(rev)) with IC50 of 5.7 μM. KB-R7943 mesylate promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux.
E0002	CGP-37157	CGP-37157 is a potent, selective, and specific inhibitor of mitochondrial Na(+)-Ca2+ exchanger at concentrations ≤ 10 μM.
S6920	SEA0400	SEA0400 is a selective and potent inhibitor of the Na+-Ca2+ exchanger (NCX) that inhibits Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia with IC50 of 33 nM, 5.0 nM and 8.3 nM, respectively. SEA0400 prevents sodium nitroprusside (SNP) from increasing ERK and p38 MAPK phosphorylation and production of reactive oxygen species (ROS) in an extracellular Ca(2+)-dependent manner.
S0406^New	Benzylamiloride hydrochloride	Benzylamiloride hydrochloride (Benzamil hydrochloride) is an inhibitor of Na⁺/Ca²⁺ exchanger (NCX) with an IC50 ~100 nM. It reduces hyponatremic brain edema by blocking sodium influx in vivo.
S4353	Terfenadine	Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
S0016	SN-6	SN-6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor. SN-6 inhibits NCX1, NCX2, and NCX3 with IC50 of 2.9 μM, 16 μM and 8.6 μM, respectively. SN-6 abolishes acetylcholine (ACh)-induced vasodilation.
S4643	KB-R7943 mesylate	KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCX(rev)) with IC50 of 5.7 μM. KB-R7943 mesylate promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux.
E0002	CGP-37157	CGP-37157 is a potent, selective, and specific inhibitor of mitochondrial Na(+)-Ca2+ exchanger at concentrations ≤ 10 μM.
S6920	SEA0400	SEA0400 is a selective and potent inhibitor of the Na+-Ca2+ exchanger (NCX) that inhibits Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia with IC50 of 33 nM, 5.0 nM and 8.3 nM, respectively. SEA0400 prevents sodium nitroprusside (SNP) from increasing ERK and p38 MAPK phosphorylation and production of reactive oxygen species (ROS) in an extracellular Ca(2+)-dependent manner.
S0406^New	Benzylamiloride hydrochloride	Benzylamiloride hydrochloride (Benzamil hydrochloride) is an inhibitor of Na⁺/Ca²⁺ exchanger (NCX) with an IC50 ~100 nM. It reduces hyponatremic brain edema by blocking sodium influx in vivo.
S4353	Terfenadine	Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
S0016	SN-6	SN-6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor. SN-6 inhibits NCX1, NCX2, and NCX3 with IC50 of 2.9 μM, 16 μM and 8.6 μM, respectively. SN-6 abolishes acetylcholine (ACh)-induced vasodilation.
S0406^New	Benzylamiloride hydrochloride	Benzylamiloride hydrochloride (Benzamil hydrochloride) is an inhibitor of Na⁺/Ca²⁺ exchanger (NCX) with an IC50 ~100 nM. It reduces hyponatremic brain edema by blocking sodium influx in vivo.

NCX阻害剤の選択性比較

Tags: NCX inhibitor|NCX agonist|NCX activator|NCX inducer|NCX antagonist|NCX signaling pathway|NCX assay kit