LC3 antagonist | LC3 inhibitor | LC3 agonist

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S7683	PIK-III	PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates.	Cell Rep, 2024, 43(1):113575 Sci Rep, 2024, 14(1):4000 Nucleic Acids Res, 2023, gkad342
S0778	LC3-mHTT-IN-AN1	LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
E0674	Pennogenin 3-O-β-chacotrioside	Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity.
S7683	PIK-III	PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates.	Cell Rep, 2024, 43(1):113575 Sci Rep, 2024, 14(1):4000 Nucleic Acids Res, 2023, gkad342
E0674	Pennogenin 3-O-β-chacotrioside	Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity.

LC3