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S8236 MK-886 MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
Phytother Res, 2024, 10.1002/ptr.8303
Biomolecules, 2022, 12(8)1163
Int J Biochem Cell Biol, 2021, 139:106067
S8236 MK-886 MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
Phytother Res, 2024, 10.1002/ptr.8303
Biomolecules, 2022, 12(8)1163
Int J Biochem Cell Biol, 2021, 139:106067

FLAP阻害剤の選択性比較

Tags: FLAP inhibitor|FLAP agonist|FLAP activator|FLAP inducer|FLAP antagonist|FLAP signaling pathway|FLAP assay kit