Ephrin receptor

Ephrin receptor製品

• All (8)
• Ephrin receptor阻害剤 (5)
• Ephrin receptor抗体(2)
• 新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2202	NVP-BHG712	NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.	Nat Commun, 2024, 15(1):5894 Eur J Pharmacol, 2024, 983:177000 Cell Rep, 2022, 41(11):111827
S8573	Sitravatinib (MGCD516)	Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.	JCI Insight, 2022, e148717 Cancers (Basel), 2021, 13(21)5474 Cancers (Basel), 2020, 12(1)
S0256	Ehp-inhibitor-1	Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
E2835	NVP-BHG712 isomer	NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EphA2 and EphB4.
A2897	Ifabotuzumab (Anti-EphA3)	Ifabotuzumab (Anti-EphA3) is a monoclonal antibody against EphA3. MW: 145.28 KD.
E0614	AWL-II-38.3	AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
A2511	Anti-EphA2 (MEDI-547)	Anti-EphA2 (MEDI-547) is a fully human IgG1 monoclonal antibody that is used for targeting EphA2. It selectively binds to cells expressing the EphA2 receptor. MW: 145.12 KD.
S6515	ALW II-41-27	ALW II-41-27 (compound 7) is a potent inhibitor of Eph receptor tyrosine kinase with Kd of 12 nM for EphA2.
S2202	NVP-BHG712	NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.	Nat Commun, 2024, 15(1):5894 Eur J Pharmacol, 2024, 983:177000 Cell Rep, 2022, 41(11):111827
S8573	Sitravatinib (MGCD516)	Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.	JCI Insight, 2022, e148717 Cancers (Basel), 2021, 13(21)5474 Cancers (Basel), 2020, 12(1)
S0256	Ehp-inhibitor-1	Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
E0614	AWL-II-38.3	AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
S6515	ALW II-41-27	ALW II-41-27 (compound 7) is a potent inhibitor of Eph receptor tyrosine kinase with Kd of 12 nM for EphA2.
A2897	Ifabotuzumab (Anti-EphA3)	Ifabotuzumab (Anti-EphA3) is a monoclonal antibody against EphA3. MW: 145.28 KD.
A2511	Anti-EphA2 (MEDI-547)	Anti-EphA2 (MEDI-547) is a fully human IgG1 monoclonal antibody that is used for targeting EphA2. It selectively binds to cells expressing the EphA2 receptor. MW: 145.12 KD.

Ephrin receptorシグナル伝達経路