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Gamma-secretase

Gamma-secretase製品

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  • Gamma-secretase阻害剤 (2)
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製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S8185 FPS-ZM1 FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
Clin Immunol, 2024, 262:110178
Pharmacol Res, 2023, 192:106791
Cell Death Dis, 2023, 14(12):825
S7169 Crenigacestat (LY3039478) Crenigacestat (LY3039478) is an oral Notch and gamma-secretase inhibitor with IC50 of 0.41 nM for Notch.
Cell Death Dis, 2024, 15(1):53
MedComm (2020), 2023, 4(5):e346
MedComm -2020), 2023, 4(5):e346
S8185 FPS-ZM1 FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
Clin Immunol, 2024, 262:110178
Pharmacol Res, 2023, 192:106791
Cell Death Dis, 2023, 14(12):825
S7169 Crenigacestat (LY3039478) Crenigacestat (LY3039478) is an oral Notch and gamma-secretase inhibitor with IC50 of 0.41 nM for Notch.
Cell Death Dis, 2024, 15(1):53
MedComm (2020), 2023, 4(5):e346
MedComm -2020), 2023, 4(5):e346

Gamma-secretase阻害剤の選択性比較

Gamma-secretaseシグナル伝達経路

Gamma-secretaseシグナル伝達経路
Tags: Gamma-secretase inhibition | Gamma-secretase inhibitor Notch | Gamma-secretase activity | Gamma-secretase assay | Gamma-secretase cleavage | Gamma-secretase inhibitor in clinical trial | Gamma-secretase inhibitor review