PDK

亜型選択性的な製品

シグナル伝達経路

PDKシグナル伝達経路

PDK製品

  • All (6)
  • PDK阻害剤 (2)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S0983 JX06 JX06 is a selective covalent inhibitor of PDK1 in cells. JX06 dose-dependently inhibits PDK1, PDK2 and PDK3 with IC50 0.049 μM, 0.101 μM and 0.313 μM, respectively.
Biochem Biophys Res Commun, 2021, 587:153-159
F1103New PDK1 Rabbit mAb PDK1 Rabbit mAb recognizes endogenous levels of total PDK1 protein.
F0401New Phospho-PDK1 (Ser241) Rabbit mAb Phospho-PDK1 (Ser241) Rabbit mAb detects PDK1 only when phosphorylated at Ser241.
F2759New PDK4 Rabbit mAb
F2345New PDK2 Rabbit mAb
S2949 KPLH1130 KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses.

PDK阻害剤の選択性比較

阻害剤 Citation PDK1 PDK2 PDK3
KPLH1130 0
JX06 1
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Tags: PDK kinase | PDK assay | PDK activation | PDK phosphorylation | PDK cancer | PDK signaling | PDK inhibitor review