Sintilimab (anti-PD-1)

製品コード：A2035         Batch: A203503

印刷

Sintilimab (anti-PD-1, IBI 308) is a fully human IgG4 monoclonal antibody that binds to PD-1 on the surface of T-cells, blocks the PD-1/PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells.

製品説明

CAS No. 2072873-06-2
Formulation PBS Buffer, PH 7.4
Isotype Human IgG4, κ
Source CHO cells
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 6.002mg/ml
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Intratumoral CXCL13+ CD160+ CD8+ T cells promote the formation of tertiary lymphoid structures to enhance the efficacy of immunotherapy in advanced gastric cancer [ J Immunother Cancer, 2024, 12(9)e009603] PubMed: 39244216

人間や獣医の診断であるか治療的な使用のためにでない。