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Synonyms | LPSs, Endotoxin,LPS | Storage (From the date of receipt) |
3 years -20°C powder | |
化学式 | ||||
分子量 | CAS No. | 93572-42-0 | ||
Solubility (25°C)* | 体外 | Water | 15 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Lipopolysaccharides (LPSs, Endotoxin,LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consists of an antigen O-specific chain, a core oligosaccharide and lipid A. Lipopolysaccharides is a pathogenic associated molecular pattern (PAMP) that activates the immune system. Lipopolysaccharides activates TLR-4 on immune cells. Lipopolysaccharides induces secretion of cell migrasome. |
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Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells [ Int Immunopharmacol, 2024, 137:112426] | PubMed: 38878491 |
Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling [ Biomolecules, 2024, 14(7)741] | PubMed: 39062456 |
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis [ Sci Rep, 2024, 14(1):13102] | PubMed: 38849409 |
ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2 [ EMBO J, 2023, e113118.] | PubMed: 37646198 |
Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways [ Oxid Med Cell Longev, 2022, 2022:4557532] | PubMed: 35355867 |
Dichotomous Roles ofMen1in Macrophages and Fibroblasts in Bleomycin—Induced Pulmonary Fibrosis [ Int. J. Mol. Sci., 2022, 23(10), 5385] | PubMed: None |
Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice [ Front Pharmacol, 2021, 12:627123] | PubMed: 33762947 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。