Avelumab (anti-PD-L1)

製品コード：A2015         Batch: A201506

印刷

Avelumab (anti-PD-L1) (MSB0010718C) is a fully human IgG1 monoclonal antibody that targets the protein programmed death-ligand 1 (PD-L1). Avelumab exhibits potential antibody-dependent cell-mediated cytotoxicity and is used for the treatment of several kinds of carcinoma. MW=143.8 kDa.

製品説明

CAS No. 1537032-82-8
Formulation 100 mM Pro-Ac, 20 mM Arg, pH 5.0
Isotype Human IgG1
Source Human
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 8.27mg/ml
Endotoxin Level ＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker [ J Biol Chem, 2024, S0021-9258(24)01826-X] PubMed: 38685532
TNF-Mediated Inhibition of Classical Swine Fever Virus Replication Is IRF1-, NF-κB- and JAK/STAT Signaling-Dependent [ Viruses, 2021, 13(10)2017] PubMed: 34696447

人間や獣医の診断であるか治療的な使用のためにでない。