Anti-mouse PD-1 (CD279)-InVivo

製品コード：A2122         Batch: A212226

印刷

Anti-mouse PD-1 (CD279)-InVivo (Clone:RMP1-14)reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily.

製品説明

Formulation PBS Buffer, PH 7.4
Clone RMP1-14
Isotype Rat IgG2a, κ
Source CHO
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C and avoid freeze-thaw cycle
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 9.77 mg/mL
Endotoxin Level ＜1 EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Radiotherapy-resistant prostate cancer cells escape immune checkpoint blockade through the senescence-related ataxia telangiectasia and Rad3-related protein [ Cancer Commun (Lond), 2024, 10.1002/cac2.12636] PubMed: 39698847
Targeting tumor-associated macrophage-derived CD74 improves efficacy of neoadjuvant chemotherapy in combination with PD-1 blockade for cervical cancer [ J Immunother Cancer, 2024, 12(8)e009024] PubMed: 39107132
Durable antitumor response via an oncolytic virus encoding decoy-resistant IL-18 [ J Immunother Cancer, 2024, 12(12)e009716] PubMed: 39631848
Candida albicans-myeloid cells-T lymphocytes axis in the tumor microenvironment of oral tumor-bearing mice [ Cancer Lett, 2024, 588:216814] PubMed: 38499264
ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma [ Cell Rep, 2024, 43(11):114962] PubMed: 39522165
CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Transl Lung Cancer Res, 2024, 13(5):1032-1046.] PubMed: 38854937
CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Transl Lung Cancer Res, 2024, 13(5):1032-1046] PubMed: 38854937

人間や獣医の診断であるか治療的な使用のためにでない。