Anti-mouse CD8α-InVivo

製品コード：A2102         Batch: A210221

印刷

Anti-mouse CD8α (Clone:2.43)reacts with mouse CD8α. CD8 is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). It binds to class I MHC molecules displayed by antigen presenting cells (APC).

製品説明

Formulation PBS buffer, pH 7.0
Clone 2.43
Immunogen Mouse CTL clone L3
Isotype Rat IgG2b, κ
Application In vivo CD8+ T cell depletion,WB
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 4.54 mg/mL
Endotoxin Level ＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway [ J Immunother Cancer, 2025, 13(2)e010252] PubMed: 39915005
Disulfiram/copper triggers cGAS-STING innate immunity pathway via ROS-induced DNA damage that potentiates antitumor response to PD-1 checkpoint blockade [ Int J Biol Sci, 2025, 21(4):1730-1748] PubMed: 39990655
Tetrandrine augments melanoma cell immunogenicity via dual inhibition of autophagic flux and proteasomal activity enhancing MHC-I presentation [ Acta Pharmacol Sin, 2025, 10.1038/s41401-025-01507-9] PubMed: 40016522
cGAS-activated endothelial cell-T cell cross-talk initiates tertiary lymphoid structure formation [ Sci Immunol, 2024, 9(98):eadk2612] PubMed: 39093956
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity [ Cell Rep Med, 2024, 5(5):101533] PubMed: 38744278
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity [ Cell Rep Med, 2024, 5(5):101533] PubMed: 38744278
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade [ J Immunother Cancer, 2024, 12(9)e009327] PubMed: 39244215
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer [ Cancer Lett, 2024, 589:216836.] PubMed: 38556105
Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment [ Cell Rep, 2024, 43(9):114697] PubMed: 39217611
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function [ Cell Oncol (Dordr), 2024, 10.1007/s13402-024-00959-1] PubMed: 38809326

人間や獣医の診断であるか治療的な使用のためにでない。